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 Meiosis I in spermatocytes

 

Male Drosophila gonial stem cells undergo four rounds of mitosis whereby cysts of 16 early spermatocytes are formed. These grow to a size 25 times the original size before they start the first meotic division. During meiosis I spermatocytes have large spindles and thus are well suited for spindle assembly and chromosome segregation studies. In addition, the nuclear envelope does not completely break down during the division stages, allowing for the study of different intra- and extranuclear sets microtubules. Time-lapse confocal microscopy videos of these cells, labeled with fluorescent chimeras for microtubules and centrosomal components, are provided in this section.
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